Description

Flexagon™ Gel is a newly formulated blend of 100% pain relief herbal oils designed for use in managing pain, swelling and other muscle and joints associated ailments.

The new and improved Flexagon™ Gel is a mixture of 10 novel essential oils that have been proven and validated as useful in relieving pain associated with arthritis, muscle and joint trauma.   The powerful herbal ingredients present penetrates deep into the skin and act on the pain area effectively, providing instant and long-lasting relief with no side effects for all ages.

BENEFITS

• Synergistic effects of more than 10 essential oils
• Help relieve the swelling, stiffness and pain.
• A 100% herbal preparation,
• It is uniquely formulated to act fast
• The ingredients used are not known to cause adverse effects when applied as advised on the user instructions

HOW IT WORKS

• The molecules of essential oils in Flexagon are so small that when applied to the skin, they easily pass through the outer layer of skin known as the stratum corneum.
• From there the molecules pass through the inner layer of the skin (dermis) from where they enter into the blood circulatory system and reach the source of pain.
• The chemical constituents of the essentials oils in Flexagon™ gel are known to possess anti-arthritic potential through modulation of the levels of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6

SCIENTIFIC REFERENCE

1. Funk JL, Frye JB, Oyarzo JN, Chen J, Zhang H, Timmermann BN. Anti-Inflammatory Effects of the Essential Oils of Ginger (Zingiber officinale Roscoe) in Experimental Rheumatoid Arthritis. PharmaNutrition. 2016 Jul;4(3):123-131. doi: 10.1016/j.phanu.2016.02.004.
2. Sharma S, Arif M, Nirala RK, Gupta R, Thakur SC. Cumulative therapeutic effects of phytochemicals in Arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress. J Sci Food Agric. 2016 Mar 30;96(5):1500-10. doi: 10.1002/jsfa.7252.
3. Silva J, Abebe W, Sousa SM, Duarte VG, Machado MI, Matos FJ. Analgesic and anti-inflammatory effects of essential oils of Eucalyptus. J Ethnopharmacol. 2003 Dec;89(2-3):277-83. doi: 10.1016/j.jep.2003.09.007.
4. Xiao S, Yu H, Xie Y, Guo Y, Fan J, Yao W. The anti-inflammatory potential of Cinnamomum camphora (L.) J.Presl essential oil in vitro and in vivo. J Ethnopharmacol. 2021 Mar 1;267:113516. doi: 10.1016/j.jep.2020.113516.
5. Hernández-Cruz EY, Silva-Islas CA, Maldonado PD, Pedraza-Chaverri J, Carballo-Villalobos AI. Antinociceptive effect of garlic, garlic preparations and derivative compounds. Eur J Pain. 2022 May;26(5):947-964. doi: 10.1002/ejp.1935.
6. Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian J Pharm Sci. 2011 May;73(3):255-61. doi: 10.4103/0250-474X.93507. PMID: 22457547; PMCID: PMC3309643.
7. Chattopadhyay P, Hazarika S, Dhiman S, Upadhyay A, Pandey A, Karmakar S, Singh L. Vitex negundo inhibits cyclooxygenase-2 inflammatory cytokine-mediated inflammation on carrageenan-induced rat hind paw edema. Pharmacognosy Res. 2012 Jul;4(3):134-7. doi: 10.4103/0974-8490.99072..
8. Aslam A, Nokhala A, Peerzada S, Ahmed S, Khan T, Siddiqui MJ. Evaluation and Comparison Fof Trachyspermum ammi Seed Extract for Its Anti-inflammatory Effect. J Pharm Bioallied Sci. 2020 Nov;12(Suppl 2):S777-S780. doi: 10.4103/jpbs.JPBS_243_19.
9. Bahr T, Allred K, Martinez D, Rodriguez D, Winterton P. Effects of a massage-like essential oil application procedure using Copaiba and Deep Blue oils in individuals with hand arthritis. Complement Ther Clin Pract. 2018 Nov;33:170-176. doi: 10.1016/j.ctcp.2018.10.004. Hebert PR, Barice EJ, Hennekens CH. Treatment of low back pain: the potential clinical and public health benefits of topical herbal remedies. J Altern Complement Med. 2014 Apr;20(4):219-20. doi: 10.1089/acm.2013.0313.